摘要
登革熱是最流行的蚊蟲媒病感染，全世界每年發生超過3.9億例登革熱感染。登革熱病毒感染的表現形式廣泛，從高熱病到登革出血熱或登革熱休克綜合徵。也描述了涉及心臟，肝臟，中樞神經系統和肺部的非典型表現。在這裡，我們報告一嚴重的登革熱伴急性肝炎和急性呼吸窘迫綜合徵之案例。一名76歲的女性入院10天，出現發燒，血小板減少症，肝功能指數升高，肝性腦病變，急性腎功能衰竭和急性呼吸困難，被診斷為急性呼吸窘迫綜合徵。由於頑固性休克和多重器官功能衰竭，她的病情隨後惡化並最終死亡。我們回顧了有關急性肝炎和急性呼吸窘迫綜合徵的登革熱病毒感染的文獻。
關鍵詞：登革熱； 急性肝炎； 急性呼吸窘迫綜合徵
Abstract
Dengue fever is the most prevalent arboviral infection with more than 390 million dengue infections throughout the world annually. Dengue virus infections have a wide range of manifestations from febrile illness, dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS) to atypical manifestations related to hearts, livers, central nerve systems or lungs. Here, we report a case of severe dengue fever with acute hepatitis and acute respiratory distress syndrome (ARDS). A 76-year-old female was admitted for 10 days. She developed fever, thrombocytopenia, liver function elevation, hepatic encephalopathy, acute renal failure and acute breathlessness. She was diagnosed to be ARDS. Her condition deteriorated and eventually died due to refractory shock with multiple organ failures. We review the literature on dengue virus infections with acute hepatitis and ARDS.
Keywords: Dengue Fever, Acute Hepatitis, Acute Respiratory Distress Syndrome